We are back with another great ASK the Vet episode where Heather is speaking with Dr. Julia Montgomery associate professor of large animal clinical sciences from the Western College of Veterinary Medicine in Saskatchewan Canada. The topic we are reviews is PPID Pituitary pars intermedia dysfunction (PPID; equine Cushing’s disease). The disease of the again horse that once they have it they have it for the rest of their life.
We discuss, who is at risk, signs, and warnings, and how it is tested for. Like many other diseases that affect horses, there are 3 levels of PPID, mild, moderate, and severe. Join us to learn all about this disease and how you can manage your horse if they get it.
Ask the Vet – What is PPID or Cushing’s disease
Pituitary pars intermedia dysfunction (PPID; equine Cushing’s disease) is an endocrine disorder that occurs in over 20% of aged horses, ponies, and donkeys. Most animals are over 15 years old when diagnosed, but PPID can occur in younger horses. It is, rare in horses less than 10 years old. Horses and ponies of any breed may be affected.
PPID – whats is actually happening
The pituitary gland, located at the base of the brain, plays a key role in regulating the body’s hormones. Many metabolic and reproductive functions, as well as blood pressure and electrolyte balance can be affected. Horses develop enlargement and benign tumors in a section of the pituitary gland known as the pars intermedia. While these tumors do not spread and rarely become large enough to cause neurological disease, they overproduce hormones that create an abnormal metabolic state.
Ask the Vet – What does a horse with PPID look like
The most obvious sign of PPID is a distinct, shaggy hair coat, called hypertrichosis. Some horses can develop this long hair coat over their entire body, while others have localized patches of long hair, or just some longer hairs around the jawlines and lower limbs. These horses also can have delayed shedding in the spring or will not shed out at all. Other common, but less obvious, signs of PPID include increased thirst (polydipsia), increased urination (polyuria), and muscle wasting.
Ask the Vet – How to treat PPID
Pergolide mesylate is a drug that acts on receptors within the pars intermedia to suppress tissue enlargement and tumor growth. The only formulation currently approved by the Food and Drug Administration for the treatment of PPID in horses is Prascend.®
Ask the Vet – What to feed
Pelleted senior feeds are effective for maintaining or gaining weight. If needed, fat supplements can be added to provide extra calories for horses that need to gain weight. For horses with insulin dysregulation, dietary sugar restriction are also needed and can be done by eliminating grain and limiting pasture access, especially during spring and fall when grass sugar content is higher.
Julia Montgomery (Canada)
Information on Julia can be found at Julia Montgomery Published
Don’t forget to check out the resources section in this article!
- Abnormal Shedding
- Muscle wasting
- Loss of top line
- Challenge to catch in early cases
Thank you for tuning in and happy trails!
Calling all equestrians! Elkhorn Ranch’s tradition of equestrian adventure began 99-years-ago in 1922. Bordering Yellowstone National Park, the history of Elkhorn’s riding program runs deep, and the backcountry is where it starts. This Fall, we are hosting an Avid Riders week, where we are rounding up experienced riders of varying disciplines to come together to explore over one million acres of National Forest, USFS Wilderness, and Yellowstone National Park.
The goal of this week is to go far, not fast. Every day there will be groups that will hit the trails in every direction based on desired time in the saddle and comfort level. We will be racking up the mileage this week and working our way into the backcountry for mountaintop vistas that not many can get to.
All riders must be willing to ride on rocky and steep terrain, as well as comfortable with walk, trot, and canter. Our horses are well mannered and smart mountain horses, if you trust them, they will take you wherever you want to go.
Please reach out to Kt at firstname.lastname@example.org Rates include all meals, cabin lodging, and all on-ranch activities.
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- Julia Montgomery published
- Equine Health
- Photo’s of PPID
- PPID Cushing disease
- Equine Metabolic Syndrome
- EQUINE ENDOCRINOLOGY
- American College of Veterinary Medicine
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- Equestrian tools and resources
- EQA Online Shop